What Is the Evidence to Suggest That Dopamine Plays an Important

What is the evidence to suggest that dopamine plays an important role in depression?

A) Typical antidepressant drugs quickly but modestly increase dopamine levels in the limbic system.
B) Dopamine levels increase with chronic typical antidepressant use, possibly accounting for the delayed treatment response of these drugs.
C) Typical antidepressants target dopamine receptors in the limbic system, albeit with lower affinity than for serotonin or norepinephrine transporters.
D) Typical antidepressants are less effective in transgenic mice that synthesize very low levels of dopamine.