According to conditioned place preference and self administration studies described in the text (Popik and Kolasiewicz, 1999; LaLumiere and Kalivas, 2008), which neurotransmitter has an important role in the reinforcing effects of opioids?
A) glutamate
B) serotonin
C) adenosine
D) epinephrine

Question

Quizplus · Accepted Answer

Glutamate plays a significant role in the reinforcing effects of opioids, as indicated by conditioned place preference and self-administration studies. These studies suggest that the interaction between opioids and the glutamatergic system is crucial for the development of opioid addiction.

According to Conditioned Place Preference and Self Administration Studies Described