Dr. Arnold is excited to discover the relationship between GHB and dopamine release. What does he find?
A) Both low and high doses lead to increased dopamine levels in the long-term.
B) Both low and high doses lead to decreased dopamine levels in the long-term.
C) Low doses decrease dopamine release; high doses eventually increase dopamine levels.
D) Low doses increase dopamine release; high doses eventually decrease dopamine levels.

Question

Quizplus · Accepted Answer

Low doses of GHB have been found to decrease dopamine release, while high doses can initially decrease dopamine release but eventually lead to an increase in dopamine levels. This biphasic effect is due to GHB's complex action on the brain, including its interactions with GABA-B receptors and its role in the modulation of dopaminergic systems.

Dr Arnold Is Excited to Discover the Relationship Between GHB