What is the effect of deletion of the locus control region for the b-globin gene cluster?
A) Loss of fetal hemoglobin expression
B) Reduced expression of hemoglobin
C) Absent expression of all of the hemoglobin genes in the cluster
D) Overexpression of all of the hemoglobin genes in the cluster
E) Inappropriate expression of fetal and embryonic hemoglobin after birth
Correct Answer:
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Q2: Which of the following types of mutations
Q3: Why can a-globin mutations have an
Q4: Which clinical phenotype is associated with an
Q5: At which stage can a mutation disrupt
Q6: Which of the following is the most
Q7: Why is hydrops fetalis largely restricted
Q8: Which clinical phenotype is associated with a
Q10: In addition to mutations in a
Q11: Four sites associated with what type of
Q12: A transition between which two hemoglobin
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