Iron overload in severe b-thalassemia (b-thalassemia major)patients is primarily a consequence of

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Patients with $\beta$-thalassemia major have a severe anemia;many of their clinical problems are related to this anemia.Giving the patient massive red cell transfusion therapy can ameliorate some of these clinical problems.Unfortunately,a serious consequence of this is the build up of iron in the body from all the transfused RBCs because the body has no mechanism for excreting iron.

Iron Overload in Severe B-Thalassemia (B-Thalassemia Major)patients Is Primarily a Consequence