What are the abnormalities in cytokines found in children with cystic fibrosis (CF)?
A) Deficit of interleukin (IL)-1 and an excess of IL-4, IL-12, and interferon-alpha (IFN-α)
B) Deficit of IL-6 and an excess of IL-2, IL-8, and granulocyte colony-stimulating factor (G-CSF)
C) Deficit of IL-10 and an excess of IL-1, IL-8, and TNF-α
D) Deficit of IL-3 and an excess of IL-14, IL-24, and colony-stimulating factor (CSF)

Question

Quizplus · Accepted Answer

Abnormal cytokine profiles have been documented in CF airway fluids,including deficient IL-10 and excessive IL-1,IL-8,and TNF-α,all changes conducive to promoting inflammation.This selection is the only option that accurately identifies the abnormalities in cytokines observed in children with CF.

What Are the Abnormalities in Cytokines Found in Children with Cystic