The stronger the antigen difference, the more severe the graft-versus-host reaction.

Question

Quizplus · Accepted Answer

The severity of graft-versus-host disease (GVHD) is influenced by the degree of mismatch between the donor's and recipient's human leukocyte antigens (HLAs). A stronger antigen difference typically leads to a more severe immune response, as the donor's immune cells are more likely to recognize the recipient's cells as foreign and attack them.

The Stronger the Antigen Difference, the More Severe the Graft-Versus-Host