Prognostic markers that may help identify patients with more severe RA who are still in the early stages of the disease include the presence of certain HLA class I alleles.

Question

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Prognostic markers for more severe RA (Rheumatoid Arthritis) in early stages often include the presence of certain HLA class II alleles (e.g., HLA-DRB1), not class I alleles. HLA class II alleles are associated with disease susceptibility and severity.

Prognostic Markers That May Help Identify Patients with More Severe