Some cases of human melanoma have been shown to result from inhibition of apoptosis in these cells. The human analogue of which of the following defects in C. elegans could cause these cancers?
A) A ced-9 protein that is always inactive.
B) A ced-3 protein that is always inactive.
C) A ced-4 protein that is always active.
D) A death-signaling molecule receptor that is always active.

Question

Quizplus · Accepted Answer

In C. elegans, the ced-3 protein is crucial for the initiation of apoptosis. If ced-3 is always inactive, apoptosis would be inhibited, potentially leading to uncontrolled cell growth and cancer in humans, similar to the effect seen in some melanoma cases.

Some Cases of Human Melanoma Have Been Shown to Result