A change of a single amino acid at a position distant from the active site of an enzyme can alter the substrate specificity by changing the ________.
A) by changing the intracellular location of the enzyme
B) by changing the 3-D shape of the enzyme
C) by changing the stability the enzyme
D) by changing the binding site for a competitive inhibitor

Question

Quizplus · Accepted Answer

A single amino acid change, even at a position distant from the active site, can alter the enzyme's 3-D shape (tertiary structure), potentially affecting substrate specificity by altering how the substrate fits into the active site.

A Change of a Single Amino Acid at a Position