Which of the following best describes a biological concern regarding the use of CRISPR-Cas9 gene editing in humans?
A) The process may introduce viral sequences into the human genome leading to unwanted blood cell proliferation (leukemia).
B) The presence of repeated sequences (STRs) within the human genome mean that the editing cannot be targeted to a specific location.
C) The process was first discovered in bacteria and human cells cannot correctly interpret prokaryotic regulatory signals.
D) The modifications created by the process may result in unintended effects on non-target genes.

Question

Quizplus · Accepted Answer

The primary biological concern with CRISPR-Cas9 gene editing is off-target effects, where edits occur in unintended parts of the genome, potentially disrupting or altering the function of non-target genes. This can lead to unintended consequences, including the possibility of causing diseases or disorders.

Which of the Following Best Describes a Biological Concern Regarding