Which of the following correctly describes a Philadelphia chromosome?
A) a human chromosome 22 that has had a specific translocation from chromosome 9
B) a human chromosome 9 that is found only many types of cancer
C) a chromosome found only in mitochondria
D) a chromosome with a point mutation that increases cell division

Question

Quizplus · Accepted Answer

The Philadelphia chromosome is characterized by a specific genetic abnormality, which is a translocation between chromosome 9 and chromosome 22. This translocation results in the fusion of the BCR gene on chromosome 22 with the ABL gene on chromosome 9, leading to the formation of a hybrid gene known for its association with chronic myeloid leukemia (CML) and other types of cancer.

Which of the Following Correctly Describes a Philadelphia Chromosome