Endocrine hormones function to not only affect a target tissue, but to cause a subsequent decrease in the continued release of more of the same hormone. This mechanism that limits the amount of a hormone response that occurs is called:

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Quizplus · Accepted Answer

Negative feedback is the mechanism by which the endocrine system regulates hormone levels to maintain homeostasis. When a hormone is released and has its effect on target tissues, the response often leads to a decrease in the further release of that hormone, thus preventing overactivity of the hormone's effects.

Endocrine Hormones Function to Not Only Affect a Target Tissue