Why is levothyroxine (T 4 ) preferred for treatment of hypothyroidism than liothyronine (T 3 )?

Levothyroxine (T 4 ) is preferred for the treatment of hypothyroidism because it is a prohormone that is converted into the active hormone liothyronine (T 3 ) in the body, thus participating more effectively in the body's natural thyroid hormone feedback loop.

Why is levothyroxine (T 4 ) preferred for treatment of hypothyroidism than liothyronine (T 3 )?

Levothyroxine (T 4 ) is preferred for the treatment of hypothyroidism because it is a prohormone that is converted into the active hormone liothyronine (T 3 ) in the body, thus participating more effectively in the body's natural thyroid hormone feedback loop.

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Why Is Levothyroxine (T₄) Preferred for Treatment of Hypothyroidism Than

Question 21

Multiple Choice

Why is levothyroxine (T₄) preferred for treatment of hypothyroidism than liothyronine (T₃) ?

A) T₃ is a synthetic drug, while T₄ is natural
B) T₃ is never used in clinical cases
C) T₄ is much cheaper than T₃
D) T₄ has a much shorter half-life than T₃, so it's potentially more toxic
E) T₄ appears more of a factor in the negative feedback loop than T₃