In a well-designed study, a statistically significant increase in maximal strength with creatine supplementation was detected at 12 weeks but not at 1 week. What is the likely explanation?
A) Creatine supplementation allowed athletes to complete more weight lifting repetitions and sets, but the effects of the training are not seen immediately.
B) It takes time (about three months) for the body to increase the total amount of ATP stored in muscle.
C) Time was needed to maximize carbohydrate stores because creatine storage and function are directly related to the size of muscle glycogen stores.
D) Hormonal balance is altered, but the changes are slow and subtle and not detectable for approximately 12 weeks.
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