High-frequency stimulation of a skeletal muscle causes tetanic contraction because the intracellular concentration of which of the following substances increases and remains at high levels?
A)Adenosine triphosphate
B)Calcium
C)Potassium
D)Sodium
E)Troponin

Question

Quizplus · Accepted Answer

High-frequency stimulation of a skeletal muscle causes tetanic contraction because it leads to an increase in intracellular calcium concentration. Calcium plays a critical role in muscle contraction by binding to troponin and allowing the myosin heads to bind to actin, leading to sliding of the filaments and muscle contraction. The sustained elevation of calcium, as seen during tetanic contractions, leads to sustained muscle contraction.

High-Frequency Stimulation of a Skeletal Muscle Causes Tetanic Contraction Because