During DNA replication in the cell, DNA primase makes short primers that are then extended by the replicative DNA polymerases. These primers …
A) are made up of DNA.
B) generally have a higher number of mutations compared to their neighboring DNA.
C) are made more frequently in the leading strand than the lagging strand.
D) are joined to the neighboring DNA by DNA ligase.
E) provide a 3′-phosphate group for the DNA polymerases to extend.

Question

Quizplus · Accepted Answer

The DNA primase enzyme syntheses RNA primers (with free 3′-OH groups) that are extended and later replaced by DNA that is more accurately synthesized. This happens more frequently in the lagging strand.

During DNA Replication in the Cell, DNA Primase Makes Short