The sliding clamp and the DNA helicase that function at the replication fork both have three-dimensional structures resembling a ring with a central hole through which DNA is threaded. Which of these proteins, the clamp (C) or the helicase (H), do you think has a wider hole in its structure? Write down C or H as your answer.

Question

Quizplus · Accepted Answer

The central hole in the clamp can accommodate a double-stranded DNA molecule with extra room for smooth sliding. However, the helicase only allows a single strand of DNA to pass through its central hole.

The Sliding Clamp and the DNA Helicase That Function at the Replication