Indicate whether each of the following descriptions better applies to cDNA libraries (C) or genomic DNA libraries (G). Your answer would be a five-letter string composed of letters C and G only, e.g. CGCGC.
( ) Their production requires use of reverse transcriptase.
( ) They are enriched in protein-coding genes.
( ) Different sequences are represented in them based on their transcription level.
( ) They contain intronic sequences.
( ) They are cell-type specific.

Question

Indicate whether each of the following descriptions better applies to cDNA libraries (C) or genomic DNA libraries (G). Your answer would be a five-letter string composed of letters C and G only, e.g. CGCGC.
( )	Their production requires use of reverse transcriptase.
( )	They are enriched in protein-coding genes.
( )	Different sequences are represented in them based on their transcription level.
( )	They contain intronic sequences.
( )	They are cell-type specific.

Quizplus · Accepted Answer

cDNA libraries are enriched in protein-coding genes and lack intronic sequences. They are cell-type specific; how much each gene sequence is represented in such a library depends on its level of transcription in the cell type from which the library was obtained. The cDNA is made by reverse transcription of mRNA extracted from the cell.

Indicate Whether Each of the Following Descriptions Better Applies to CDNA