Indicate true (T) and false (F) statements below regarding the nuclear transport of proteins. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTF.
( ) Many nuclear import and export receptors are members of the same protein family.
( ) Most nuclear import receptors contain unstructured domains with FG-repeats.
( ) Adaptor proteins that simultaneously bind to nuclear localization signals and to importins are required for the import of some nuclear cargo proteins.
( ) Ran is mostly found in its GTP-bound form in the nucleus.

Question

Indicate true (T) and false (F) statements below regarding the nuclear transport of proteins. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTF.
( )	Many nuclear import and export receptors are members of the same protein family.
( )	Most nuclear import receptors contain unstructured domains with FG-repeats.
( )	Adaptor proteins that simultaneously bind to nuclear localization signals and to importins are required for the import of some nuclear cargo proteins.
( )	Ran is mostly found in its GTP-bound form in the nucleus.

Quizplus · Accepted Answer

The karyopherin family includes many nuclear transport receptors and adaptors. FG-repeats are found in several proteins of the nuclear pore complex, and can interact with karyopherins. Due to the presence of Ran-GEF anchored to the nuclear chromatin, GTP-bound Ran is more abundant in the nucleus.

Indicate True (T) and False (F) Statements Below Regarding the Nuclear