Which of the following events contributes to driving the mammalian cell past the restriction point of the cell cycle?
A) Phosphorylation of Cdh1-APC/C by G₁/S-Cdk
B) Destruction of CKIs that target S-Cdks
C) Phosphorylation of Rb by G₁-Cdk, G₁/S-Cdk, and S-Cdk
D) Activation of E2F gene expression by active E2F protein
E) All of the above

Question

Quizplus · Accepted Answer

All of these processes ensure a sharp transition from G₁ to S phase, as well as sustained S-Cdk activity afterward.

Which of the Following Events Contributes to Driving the Mammalian