Overproduction of cadherins such as E-cadherin …
A) is often found in cancers originating from epithelia.
B) is induced by the transcription regulatory protein Twist.
C) induces epithelial-mesenchymal transition.
D) leads to stronger cell-cell adhesion.
E) All of the above.

Question

Quizplus · Accepted Answer

Loss of cadherin function is often found in malignant cancer cells. Twist negatively regulates cadherin and induces epithelial-mesenchymal transition. A higher level of cadherin typically leads to stronger cadherin-dependent adhesions.

Overproduction of Cadherins Such as E-Cadherin …