Multidomain glycoproteins in the extracellular matrix have binding sites for many other macromolecules. These glycoproteins …
A) can serve as tracks along which cells can migrate.
B) can bind to growth factors and influence cell signaling.
C) can bind to cell-surface receptors.
D) can serve as repellents to forbid cell migration.
E) All of the above.

Question

Quizplus · Accepted Answer

The extracellular matrix contains a large and varied set of multidomain glycoproteins such as fibronectin. They help organize the matrix and cell-matrix attachments. They also guide and control cell migration during development. Their binding to peptide growth factors and small molecules influences cell signaling within a tissue.

Multidomain Glycoproteins in the Extracellular Matrix Have Binding Sites for Many