The following schematic drawing shows two integrin molecules. Which molecule (a or b) is depicted in its active configuration? Which side of the plasma membrane (1 or 2) represents the cytosol?
A) a; 1
B) a; 2
C) b; 1
D) b; 2

Question

The following schematic drawing shows two integrin molecules. Which molecule (a or b) is depicted in its active configuration? Which side of the plasma membrane (1 or 2) represents the cytosol? 
A) a; 1 
B) a; 2 
C) b; 1 
D) b; 2

Quizplus · Accepted Answer

Integrins have two major activity states; in the active form, the large extracellular domains are more extended and further apart from each other.

The Following Schematic Drawing Shows Two Integrin Molecules