The focal adhesion kinase …
A) is a cytosolic serine/threonine kinase.
B) binds directly to integrin dimers.
C) can be phosphorylated by Src kinases.
D) prevents the relay of outside-in integrin signaling.
E) All of the above.

Question

Quizplus · Accepted Answer

Focal adhesion kinase (FAK) is a tyrosine kinase recruited to active integrins via adaptor proteins such as talin and paxillin; it is autophosphorylated and also phosphorylated by recruited Src kinases, helping to relay signals into the cell.

The Focal Adhesion Kinase …