Indicate true (T) and false (F) statements below regarding integrin signaling. Your answer would be a four-letter string composed of letters T and F only, e.g. TFTT.
( ) Integrins usually bind their ligands with a higher affinity compared to other cell-surface receptors.
( ) Unlike cadherins, integrins usually function as individual dimers and do not cluster.
( ) Anchorage dependence is mainly mediated via integrin signaling.
( ) Integrins can activate the Ras-MAPK pathway.

Question

Indicate true (T) and false (F) statements below regarding integrin signaling. Your answer would be a four-letter string composed of letters T and F only, e.g. TFTT.
( )	Integrins usually bind their ligands with a higher affinity compared to other cell-surface receptors.
( )	Unlike cadherins, integrins usually function as individual dimers and do not cluster.
( )	Anchorage dependence is mainly mediated via integrin signaling.
( )	Integrins can activate the Ras-MAPK pathway.

Quizplus · Accepted Answer

Integrins usually bind to their ligands weakly; their high concentration in the membrane and their clustering affect their collective affinity.

Indicate True (T) and False (F) Statements Below Regarding Integrin