Where are the hypervariable regions located in a typical antibody molecule?
A) Only in the N-terminal region of the light chain
B) Only in the C-terminal region of the light chain
C) Only in the N-terminal region of the heavy chain
D) Only in the C-terminal region of the heavy chain
E) In the N-terminal region of both the light and the heavy chain

Question

Quizplus · Accepted Answer

The greatest diversity in the variable regions of light and heavy chains occurs in their hypervariable regions. The actual antigen binding site is formed by only about 5-10 amino acid residues in each hypervariable region.

Where Are the Hypervariable Regions Located in a Typical Antibody