In glycogen storage disease type I, the enzyme block results in an inability to produce:

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In glycogen storage disease type I, the enzyme block affects the production of glucose. Glucose cannot be produced from glycogen stores in the liver, and this leads to low blood sugar levels (hypoglycemia) and other complications. Galactose and fructose are not directly affected by this type of glycogen storage disease. In glycogen storage disease type I, the enzyme block occurs in glucose-6-phosphatase, which is responsible for converting glucose-6-phosphate to glucose. As a result, there is an inability to produce glucose, leading to hypoglycemia and other metabolic disturbances. The inability to produce glycogen is a secondary effect of the block in glucose production. Galactose and fructose production are not affected in this type of glycogen storage disease.

In Glycogen Storage Disease Type I, the Enzyme Block Results