Absorption of _____ requires the presence of intrinsic factor.

Question

Quizplus · Accepted Answer

Absorption of vitamin B₁₂ requires the presence of intrinsic factor, which is a protein produced by the stomach. Intrinsic factor binds to vitamin B₁₂ and allows it to be absorbed in the small intestine. Without intrinsic factor, vitamin B₁₂ cannot be absorbed effectively, which can lead to a deficiency over time. The other vitamins listed do not require intrinsic factor for absorption. The absorption of vitamin B₁₂ requires the presence of intrinsic factor, a protein secreted by gastric parietal cells. Intrinsic factor binds to vitamin B₁₂ in the acidic environment of the stomach and protects it from degradation by gastric acid. The intrinsic factor-vitamin B₁₂ complex is then absorbed in the terminal ileum, the last part of small intestine, with the help of specific receptors. Without intrinsic factor, vitamin B₁₂ cannot be absorbed and can lead to pernicious anemia.

Absorption of _____ Requires the Presence of Intrinsic Factor