The respiratory system compensates for deviations in pH by adjusting the amount of carbon dioxide that is exhaled.

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The respiratory system helps to maintain acid-base balance by adjusting the amount of carbon dioxide that is exhaled. When the body's pH drops due to an increase in acid, the respiratory system increases the rate and depth of breathing to reduce the amount of carbon dioxide in the body, thereby helping to raise the pH. Conversely, when pH rises due to a decrease in acid, breathing may be slowed or shallow to retain carbon dioxide and lower the pH. This is referred to as respiratory compensation.

The Respiratory System Compensates for Deviations in PH by Adjusting