Exhibit 6A This is a reaction going on in your muscle cells right this very minute: The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics:
Typical cellular concentrations: triose phosphate isomerase = 0.1 nM
Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM
Refer to Exhibit 6A. "Restrainin" is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.4 nM, the enzyme's apparent KM for the substrate is altered to 100 µM, but the Vmax is unchanged.
A) This is a competitive inhibitor.
B) This is an uncompetitive inhibitor.
C) This is a noncompetitive inhibitor.
D) This is an irreversible inhibitor.
Correct Answer:
Verified
Q53: A Lineweaver-Burk plot is useful in the
Q54: Exhibit 6A This is a reaction going
Q55: Exhibit 6A This is a reaction going
Q56: If the y-intercept of a Lineweaver-Burk plot
Q57: The Michaelis constant determines the Vmax of
Q59: Which of the following statements regarding the
Q60: Which of the following is true concerning
Q61: Competitive inhibitors have this effect:
A) Modifying the
Q62: To study the nature of an enzyme,
Q63: Non-competitive inhibitors have this effect:
A) Modifying the
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