Which of the following best describes negative cooperativity?
A) Binding of one substrate molecule prevents the enzyme from working at all.
B) Binding of one substrate molecule inhibits the binding of a second substrate.
C) Binding of one substrate molecule enhances the binding of a second substrate.
D) Binding of one substrate molecule inhibits the binding of other effectors.

Question

Quizplus · Accepted Answer

Negative cooperativity occurs when the binding of one substrate molecule to an enzyme decreases the enzyme's affinity for binding a second substrate molecule, making it harder for subsequent substrate molecules to bind.

Which of the Following Best Describes Negative Cooperativity