The main distinguishing feature of the concerted model for the behavior of allosteric enzymes is that
A) the conformation of all subunits changes simultaneously.
B) it applies only to dimeric enzymes.
C) it involves three possible conformations for all subunits.
D) the T and R conformations exist in roughly equal amounts.

Question

Quizplus · Accepted Answer

The concerted model, also known as the Monod-Wyman-Changeux (MWC) model, posits that allosteric enzymes can exist in two states, T (tense) and R (relaxed), and that all subunits of the enzyme change their conformation simultaneously from T to R upon ligand binding, enhancing the enzyme's activity. This simultaneous shift is the main distinguishing feature of this model.

The Main Distinguishing Feature of the Concerted Model for the Behavior