The primer for in vivo DNA replication is:
A) The 3' hydroxyl of the preceding Okazaki fragment.
B) A short piece of RNA.
C) A nick made in the DNA template.
D) A primer is not always required for DNA replication.
E) All of these are true.

Question

Quizplus · Accepted Answer

A short piece of RNA serves as the primer for DNA replication. This RNA primer is synthesized by an enzyme called primase and provides the free 3' hydroxyl group that is necessary for the DNA polymerase to initiate the synthesis of the new DNA strand.

The Primer for in Vivo DNA Replication Is