Spina Bifida, Characterized by Incomplete Closure of the Spinal Cord

Spina bifida, characterized by incomplete closure of the spinal cord and its bony encasement, may be manifested by what features after birth?

A) absence of one or more digits in the hands and feet
B) wide-set eyes, a flat philtrum, and a prominent forehead
C) muscle weakness and mental handicaps
D) spastic reflexes, irritability, and tremor
E) partial or complete absence of brain tissue