A 62-Year-Old Woman Comes to the Office Due to Episodic

A 62-year-old woman comes to the office due to episodic tightness over her anterior chest for the past 6 months.  It sometimes occurs while the patient is walking or climbing stairs, but several episodes have occurred while sitting at her desk at work, which she attributes to stress.  The discomfort usually lasts 5-10 minutes and feels like muscle cramps.  She has had no shortness of breath, palpitations, lightheadedness, syncope, or lower-extremity swelling.  The patient has a history of diet-controlled diabetes mellitus diagnosed 20 years ago and anxiety disorder.  She takes low-dose aspirin, lisinopril, and atorvastatin.  She is a lifetime nonsmoker and drinks 1 or 2 glasses of wine during social gatherings.  The patient has no known drug allergies.  Her father was diagnosed with a myocardial infarction at age 60, and her mother died from a hemorrhagic stroke.  Blood pressure is 125/80 mm Hg and pulse is 72/min.  BMI is 29 kg/m².  Physical examination shows no abnormalities.  ECG shows normal sinus rhythm with no abnormal repolarization changes.  Serum creatinine is 1.1 mg/dL and hemoglobin A1c is 6.5%.  Lipid panel shows LDL of 134 mg/dL and HDL of 45 mg/dL.  The patient undergoes exercise stress testing.  She exercises for 8 minutes without chest discomfort, and exercise ECG shows no abnormal ST-segment changes.  Which of the following should be communicated to the patient regarding her stress testing results?

A) They are inconclusive because you have diabetes.
B) They are likely a false negative because you are on medical therapy.
C) They are nondiagnostic because you are female.
D) They indicate that coronary artery disease is very unlikely.
E) They indicate that you have a low risk for cardiac events in the near future.