A 3-week-old male infant with Down's syndrome is brought by his parents to your office due to feeding difficulties. According to the mother, the infant becomes short of breath and his face turns blue during feeding, and when he cries. On chest auscultation, there is a harsh holosystolic murmur heard best over the lower left sternal border. There are no rales or wheezing over the lung fields. In the long run, this infant is at increased risk of developing which of the following?

Question

A 3-week-old male infant with Down's syndrome is brought by his parents to your office due to feeding difficulties.  According to the mother, the infant becomes short of breath and his face turns blue during feeding, and when he cries.  On chest auscultation, there is a harsh holosystolic murmur heard best over the lower left sternal border.  There are no rales or wheezing over the lung fields. In the long run, this infant is at increased risk of developing which of the following?

Quizplus · Accepted Answer

Explanation: Patients with Down's syndrome are at increased risk of developing acute leukemia later in life. Other conditions which occur with a higher frequency in Down's syndrome include Alzheimer-like dementia, autism, ADHD, depressive disorder, and seizure disorder. (Choice E)Patients with Down's syndrome tend to develop Alzheimer-like dementia, and not Parkinson's disease, during the 3rd and 4th decade. Educational objective: Patients with Down's syndrome are at a higher risk of developing acute leukemia later in life.

A 3-Week-Old Male Infant with Down's Syndrome Is Brought by His