You Are Working in a Lab That Studies SnoRNAs

You are working in a lab that studies snoRNAs. You mutate the antisense sequences in a C/D box snoRNA to completely different sequences. What results do you expect compared to wild type snoRNA? Check all that apply.

A) Reduced binding of the snoRNA to the rRNA
B) Reduced methylated ribose in the rRNA
C) Reduced psuedouracil in the rRNA
D) Increased binding of the snoRNA to the rRNA
E) Increased methylated ribose in the rRNA