You work in a lab that is studying piRISCs and PIWI proteins. You have isolated piRISCs from a cell. What would be one way to identify which piRISCs are involved in cleaving TE RNA vs. those that halt transcription?
A) One of the proteins in the pRISC that halts transcription should have a nuclear localization signal.
B) One of the proteins in the pRISC that halts transcription should have nuclease activity.
C) One of the proteins in the pRISC that halts transcription should have acetylation activity.
D) One of the proteins in the pRISC that halts transcription should function as a transcription factor.

Question

Quizplus · Accepted Answer

A nuclear localization signal is necessary for proteins that function within the nucleus, such as those involved in halting transcription, indicating their role in nuclear processes rather than cytoplasmic activities like cleaving TE RNA.

You Work in a Lab That Is Studying PiRISCs and PIWI