A 48-year-old man dies in a motor vehicle crash. He had a history of intravenous drug use and had recently been released from prison. The patient's other medical conditions included hepatitis C and hypertension. On autopsy, he is found to have a small, fibrotic focus in the upper portion of the lower lobe of the right lung and a calcified right hilar lymph node. These autopsy findings are most consistent with which of the following?

Question

A 48-year-old man dies in a motor vehicle crash.  He had a history of intravenous drug use and had recently been released from prison.  The patient's other medical conditions included hepatitis C and hypertension.  On autopsy, he is found to have a small, fibrotic focus in the upper portion of the lower lobe of the right lung and a calcified right hilar lymph node.  These autopsy findings are most consistent with which of the following?

Quizplus · Accepted Answer

Eductional Objective: The Ghon complex describes the two initial sites (lower lobe of lung, ipsilateral hilar lymph node) of primary tuberculosis infection.  Over time, these sites become calcified and fibrosed and can be visualized on gross pathology and radiographic imaging (Ranke complex).

A 48-Year-Old Man Dies in a Motor Vehicle Crash