A 17-year-old girl comes to the physician with a 2-day history of painful vulvar lesions, generalized fatigue, and malaise. During this period, she has also had dysuria. She is sexually active with 2 male partners and uses condoms inconsistently. Her immunizations are up-to-date; she completed the vaccination course for human papillomavirus 2 months ago. Temperature is 38.1°C (100.6°F), pulse is 100/min, respirations are 12/min, and blood pressure is 110/70 mm Hg.Physical examination reveals bilateral inguinal lymphadenopathy and tender vesicular lesions covering the labia majora and perineum. Which of the following conditions will most likely result as a sequela of this patient's infection?

Question

A 17-year-old girl comes to the physician with a 2-day history of painful vulvar lesions, generalized fatigue, and malaise. During this period, she has also had dysuria. She is sexually active with 2 male partners and uses condoms inconsistently. Her immunizations are up-to-date; she completed the vaccination course for human papillomavirus 2 months ago. Temperature is 38.1°C (100.6°F), pulse is 100/min, respirations are 12/min, and blood pressure is 110/70 mm Hg.Physical examination reveals bilateral inguinal lymphadenopathy and tender vesicular lesions covering the labia majora and perineum.  Which of the following conditions will most likely result as a sequela of this patient's infection?

Quizplus · Accepted Answer

Eductional Objective: Primary genital herpes (herpes simplex virus type 1 or 2 infection) presents as multiple, grouped vesicles on the genitals that progress to ulcers.  Primary infections can cause systemic symptoms (eg, fever, malaise) and painful inguinal lymphadenopathy.  Because HSV can invade and lie latent in the sacral dorsal root ganglia, patients are at risk for viral reactivation and recurrent genital lesions.

A 17-Year-Old Girl Comes to the Physician with a 2-Day