A 36-year-old woman comes to the office due to painful, "reddish bumps" on her shins. She has a history of hypertension and type 2 diabetes mellitus. . A representative skin rash is shown in the image below. The lesions are tender and present predominantly on the anterior surface of the lower extremities. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Which of the following would most likely be found on liver biopsy in this patient?

Question

A 36-year-old woman comes to the office due to painful, "reddish bumps" on her shins. She has a history of hypertension and type 2 diabetes mellitus. .  A representative skin rash is shown in the image below.  The lesions are tender and present predominantly on the anterior surface of the lower extremities.  Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level.  Which of the following would most likely be found on liver biopsy in this patient?

Quizplus · Accepted Answer

Eductional Objective: Sarcoidosis is a systemic inflammatory disorder characterized by noncaseating granulomas in a variety of tissues.  Most patients develop liver involvement, which typically manifests as asymptomatic hepatomegaly with mild liver function test abnormalities.  Liver biopsy frequently demonstrates scattered noncaseating granulomas.

A 36-Year-Old Woman Comes to the Office Due to Painful