A 65-year-old man arrives at the emergency department after experiencing acute, severe right flank pain, nausea, and vomiting for the past hour. Prostate cancer and membranous nephropathy are among his medical conditions. The blood pressure is 148/60 mm Hg, and the pulse rate is 95 beats per minute. The patient appears to be in moderate pain and diaphoretic on physical examination. There is tenderness at the right costovertebral angle. Urinalysis reveals hematuria. A contrast-enhanced CT scan of the right kidney reveals a wedge-shaped perfusion defect. The affected renal tissue is most likely to develop which of the following histologic changes over the next several days?

Question

A 65-year-old man arrives at the emergency department after experiencing acute, severe right flank pain, nausea, and vomiting for the past hour. Prostate cancer and membranous nephropathy are among his medical conditions. The blood pressure is 148/60 mm Hg, and the pulse rate is 95 beats per minute. The patient appears to be in moderate pain and diaphoretic on physical examination. There is tenderness at the right costovertebral angle. Urinalysis reveals hematuria. A contrast-enhanced CT scan of the right kidney reveals a wedge-shaped perfusion defect.   The affected renal tissue is most likely to develop which of the following histologic changes over the next several days?

Quizplus · Accepted Answer

Eductional Objective: Most tissues (e.g., kidney, myocardium) undergo coagulative necrosis as a result of lethal tissue ischemia; cellular architecture is preserved, but nuclei are absent. Ischemic cell death in the CNS, which causes liquefactive necrosis, is an exception.

A 65-Year-Old Man Arrives at the Emergency Department After Experiencing