A 64-year-old guy who has been experiencing nausea and a headache that becomes worse when he leans over is now being assessed. A hemispheric cerebral mass is detected by brain imaging and is then biopsied. The picture below displays a tissue specimen under light microscopy. Which of the following histologic findings is most characteristic of this lesion?

Question

A 64-year-old guy who has been experiencing nausea and a headache that becomes worse when he leans over is now being assessed. A hemispheric cerebral mass is detected by brain imaging and is then biopsied. The picture below displays a tissue specimen under light microscopy.  Which of the following histologic findings is most characteristic of this lesion?

Quizplus · Accepted Answer

Eductional Objective: Glioblastoma multiforme is the most common primary brain tumor in adults.  Histopathology showing increased vascularity and pseudopalisading tumor cells around areas of necrosis is diagnostic.

A 64-Year-Old Guy Who Has Been Experiencing Nausea and a Headache