A 15-year-old boy is brought to the physician because of left-sided groin pain and difficulty walking for 3 weeks. He reports having pain at rest and increased pain with activity. He recently started playing flag football but does not recall any trauma. Medical history is significant for sickle cell disease. He is at the 25th percentile for height and 20th percentile for weight. His temperature is 37.0°C (98.6°F) , pulse is 90/min, and blood pressure is 120/80 mm Hg. Examination shows tenderness over the lateral aspect of the left hip with no swelling, warmth, or erythema. There is a decrease in an active and passive internal and external rotation, extension, and abduction. Imaging of the hip is shown in the exhibit.
Which of the following is the most likely cause of this patient's pain?
A) Absence of cartilage in the epiphyseal plate
B) Cytokine-mediated increased bone resorption
C) Cytokine-mediated new bone formation
D) Necrosis of bone and marrow cells
E) Synovial pannus formation
Correct Answer:
Verified
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