A 55-year-old man is found unresponsive on the street during a cold winter night. He is hypothermic and does not follow commands. Medical history is unavailable. Despite rewarming efforts, the patient dies in the emergency department. An autopsy is performed. Light microscopy of a section of the patient's kidney is shown on the slide below. This individual's renal condition could most likely have been prevented by use of which of the following types of medication?

Question

A 55-year-old man is found unresponsive on the street during a cold winter night.  He is hypothermic and does not follow commands.  Medical history is unavailable.  Despite rewarming efforts, the patient dies in the emergency department.  An autopsy is performed.  Light microscopy of a section of the patient's kidney is shown on the slide below.  This individual's renal condition could most likely have been prevented by use of which of the following types of medication?

Quizplus · Accepted Answer

Eductional Objective: Hyperplastic arteriosclerosis ("onion-skinning") and fibrinoid necrosis of the renal arterioles are typical morphologic findings in hypertensive (malignant) nephrosclerosis.  End-organ damage can be prevented by treatment of high blood pressure with antihypertensives.

A 55-Year-Old Man Is Found Unresponsive on the Street During