In the clinic, a 50-year-old man with a tenuous history of alcoholism is examined for recurrent diarrhea and weight loss. For the past two years, the patient has experienced everyday loose stools and bloating. His feces are described as oily and foul-smelling. Despite normal abdominal imaging, pancreatic insufficiency is suspected. As hormone A is administered intravenously, the patient is put through a test in which the bicarbonate content in duodenal aspirates is assessed. The graph below shows the data plotted. Hormone A is most likely produced by which of the following cell types?

Question

In the clinic, a 50-year-old man with a tenuous history of alcoholism is examined for recurrent diarrhea and weight loss. For the past two years, the patient has experienced everyday loose stools and bloating. His feces are described as oily and foul-smelling. Despite normal abdominal imaging, pancreatic insufficiency is suspected. As hormone A is administered intravenously, the patient is put through a test in which the bicarbonate content in duodenal aspirates is assessed. The graph below shows the data plotted.  Hormone A is most likely produced by which of the following cell types?

Quizplus · Accepted Answer

Eductional Objective: S cells in the duodenal mucosa release secretin in response to stimulation by intraluminal acidity. The main source of acid-neutralizing bicarbonate entering the duodenum is the exocrine pancreas, which secretes bicarbonate-rich secretions when secretin is present.

In the Clinic, a 50-Year-Old Man with a Tenuous History