Twelve families are selected for a genetic linkage study because of a high prevalence of disease. A genome screen is performed, using anonymous DNA markers on all autosomes. Significant evidence is observed for linkage to a marker on chromosome 2 (D2S123) in four families. The LOD score for the remaining families at this locus is significantly negative. How do you interpret this finding?
Correct Answer:
Verified
View Answer
Unlock this answer now
Get Access to more Verified Answers free of charge
Q1: One of the potential limitations of case-control
Q2: For some rare autosomal dominant diseases, it
Q3: Cancer of the kidney constitutes about 2%
Q4: Family history of disease is often used
Q5: A segregation analysis of a large set
Q6: Genetic linkage studies can be either based
Q8: You are interested in identifying the role
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents