Question 1

Intraepithelial neoplasia applies only to abnormal cellular transformation on the cervix.

Accepted Answer

Intraepithelial neoplasia can occur in various epithelial tissues, not just the cervix, such as the vulva, vagina, and anus.

Question 2

Worldwide, types HPV 16 and 58 are responsible for 70% of cervical cancers.

Accepted Answer

HPV types 16 and 18, not 58, are responsible for approximately 70% of cervical cancers worldwide.

Question 3

Women age 30 and older may continue to be screened with cytology alone every 3 years or with HPV testing plus cytology (cotesting) every 5 years.

Accepted Answer

The guidelines for cervical cancer screening suggest that women aged 30 and older can choose between cytology alone every 3 years or cotesting with HPV and cytology every 5 years.

Question 4

Which one of the following is not considered a risk factor for the development of CIN?

Accepted Answer

Chlamydia infection is not directly considered a risk factor for the development of cervical intraepithelial neoplasia (CIN). The other options involve conditions that compromise the immune system, which can increase the risk of CIN.

Question 5

Management of pregnant women with low-grade squamous intraepithelial lesions (LSIL) includes deferring colposcopic evaluation until 6 weeks postpartum.

Accepted Answer

Colposcopic evaluation is typically deferred until 6 weeks postpartum to allow for hormonal changes and potential resolution of LSIL during pregnancy.

Question 6

Unlike atypical squamous cells of undetermined significance (ASC-US) Pap test, the presence of atypical glandular cells Pap test necessitates referral for colposcopy not just a repeat Pap test.

Accepted Answer

Atypical glandular cells on a Pap test are more concerning than ASC-US and may indicate a higher risk of significant pathology, thus warranting further investigation with a colposcopy.

Question 7

The next step in the management of the 24-year-oldwith an ASC-US Pap is:

Accepted Answer

For a 24-year-old with ASC-US (Atypical Squamous Cells of Undetermined Significance) on a Pap test, the recommended management is to repeat the Pap test in 12 months, as per guidelines for women under 25.

Question 8

The next step in the management of women ≥ age 30 who are cytology negative but HPV positive is:

Accepted Answer

Women aged 30 and older who are cytology negative but HPV positive should have a repeat cotest (Pap and HPV test) in 12 months to monitor for any changes, as immediate colposcopy is not necessary unless there are other risk factors or abnormal findings.

Question 9

At what age do you begin Pap test screening?

Accepted Answer

Pap test screening is recommended to begin at age 21, regardless of sexual activity, and continue every 3 years through age 29.

Question 10

Women with a history of CIN 2 or greater should continue routine screening for at least 10 years after diagnosis, even if that extends beyond age 65?

Accepted Answer

The answer of Women with a history of CIN 2...

Question 11

Women who have undergone a total hysterectomy for benign conditions and have not had prior CIN 2 (moderate dysplasia) or CIN 3 (severe dysplasia or carcinoma in situ) may discontinue Pap smear screening.

Accepted Answer

Women who have had a total hysterectomy for benign reasons and have no history of high-grade cervical lesions can stop Pap smear screenings, as they no longer have a cervix.

Question 12

When performing HPV testing, both low-risk and high-risk DNA should be evaluated?

Accepted Answer

The answer of When performing HPV testing, both low-risk and...

Quiz 20: Screening for Intraepithelial Neoplasia and Cancer of the Lower Genital Tract