The BBB Defense Mechanisms in Controlling the Trafficking of Various

The BBB defense mechanisms in controlling the trafficking of various chemical moieties in and out of the brain,include:

A) complete sealing of the luminal vascular endothelial cells by tight junction protein complexes such as occludin,claudins
B) lack of fenestration in the BBB vasculature
C) astrocytic foot processes
D) efflux transport proteins ("pumps")
E) enzymatic proteins in the BBB vascular endothelia
F) All of the above
G) None of the above